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D. Kent Morest
File:D. Kent Morest, with Microscope.jpg
Dr. Morest with microscope
Born(1934-10-04)4 October 1934
Alma mater
Scientific career
Fields
Institutions

D. Kent Morest (b. October 4, 1934 in Kansas City, MO) is an American educator and researcher. He is regarded as the father of modern neuroanatomy of the auditory system [1]. His unconventional use of Golgi methods to study the neuroanatomy of the auditory nervous system in humans and mammals laid the foundation for investigations into central auditory signal processing. Other notable research interests include developmental neurobiology, and the processes related to hearing loss induced by exposure to loud noises.

Education[edit]

Morest graduated with honors from the University of Chicago in 1955. As a medical school student, he was a fellow at the Montreal Neurological Institute, a Brown Student Fellow at Yale, and a Foreign Fellow of Yale at University College London. He received his M.D. with honors from Yale University in 1960.

Professional Career[edit]

Morest is best known for his usage of the Golgi Method and detail-oriented microscopy work throughout his research career, which led to the uncovering of important advances in understanding neural structure and function. Rather than using the traditional method of presenting the cells treated with Golgi techniques as opaque blobs on a neutral background, he took the unconventional step of including illustrations of the textures, dimensions, and surfaces of the cells in his studies, which he believed allowed for a richer understanding of the microscopist’s experience.[2] He spearheaded the advancement of neuroscience (particularly auditory neuroscience) at the University of Connecticut Health Center (UCHC). He also founded the High Tech Center at UCHC. Dr. Morest was vital to the creation of the neuroscience doctoral program as well as the Department of Neuroscience at the University of Connecticut.[2]

Timeline[edit]

  • 1960-1963 Senior Assistant Surgeon, Neuroanatomical Sciences, NIH

Awards[edit]

Personal Life[edit]

In 1963, Morest married lab technician Rosemary Richtmyer. They had two children, Lydia and Claude.

Publications[edit]

Morest has authored, co-authored and edited a number of books and articles.

Selected Papers[edit]

  • Hossain WA, DSa C, Morest DK. (2006) Site-specific interactions of neurotrophin-3 and fibroblast growth factor (FGF2) in the embryonic development of the mouse cochlear nucleus. J Neurobiol 66:897-915.
  • Feng JJ, Morest DK. (2006) Development of synapses and expression of a voltage-gated potassium channel in chick embryonic auditory nuclei. Hearing Res 216-217:116-126.
  • Hossain WA, Antic SD, Yang Y, Rasband MN, Morest DK (2005) Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea. J Neurosci 25:6857– 6868.
  • Kim, J.J., Gross, J., Potashner, S.J., Morest, D.K. (2004) Fine structure of degeneration in the cochlear nucleus of the chinchilla after acoustic overstimulation. J Neurosci Res 77:798-816, 817-828, 829-842.
  • Morest DK, Cotanche DA (2004) Regeneration of the inner ear as a model of neural plasticity. J Neurosci Res 78:455-460.
  • Josephson EM, Morest DK (2003) Synaptic nests lack glutamate transporters in the cochlear nucleus of the mouse. Synapse 49:29-46.
  • Morest DK, Silver J (2003) The precursors of neurons, neuroglia, and ependymal cells in the CNS: What are they? Where are they from? How do they get where they are going? Glia 43: 6-18.
  • Hossain WA, Brumwell CL, Morest DK (2002) Sequential interactions of FGF-2, BDNF, NT-3 and their receptors define critical periods in the development of cochlear ganglion cells. Exp Neurol 175:138-151.
  • Smith L, Gross J, Morest DK (2002) Fibroblast growth factors (FGFs) in the cochlear nucleus of the adult mouse following acoustic overstimulation. Hearing Res 169:1-12.
  • Bilak MM, Hossain WA, Morest DK (2002) Intracellular fibroblast growth factor (FGF-2) produces different effects than extracellular application on development of cochleo-vestibular ganglion cells in vitro. J Neuroscience Res 71:629-647.

Books[edit]

References[edit]

  1. ^ D. Kent Morest Professional Achievement Award. Published 2014. Retrieved 10 August 2014.
  2. ^ a b CELEBRATION OF THE SCIENTIFIC CAREER OF DR. D. KENT MOREST University of Connecticut Health Center. Published October 2012. Retrieved 10 August 2014.

External links[edit]