User:Mr. Ibrahem/Armodafinil

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Mr. Ibrahem/Armodafinil
Clinical data
Pronunciationar" moe daf' i nil[1]
Trade namesNuvigil, others
AHFS/Drugs.comMonograph
MedlinePlusa602016
Pregnancy
category
  • C
Dependence
liability		Low
Routes of
administration		Oral (tablets)
Legal status
Legal status
Pharmacokinetic data
MetabolismLiver, including CYP3A4 and other pathways
Elimination half-life12–15 hours
ExcretionUrine (as metabolites)
Identifiers
  • (–)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide
Chemical and physical data
FormulaC15H15NO2S
Molar mass273.35 g·mol−1
3D model (JSmol)
  • C1=CC=C(C=C1)C(C2=CC=CC=C2)[S@](=O)CC(=O)N
  • InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1 checkY
  • Key:YFGHCGITMMYXAQ-LJQANCHMSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Armodafinil, sold under the brand name Nuvigil among others, is a medication used for narcolepsy, obstructive sleep apnea, and shift-work sleep disorder.[1] It has also been studied for tiredness associated with chronic illness.[1] It is taken by mouth.[2] It may be used recreationally for its euphoria effects.[2]

Common side effects include headache, anxiety, nausea, decreased appetite, palpitations, and disturbed sleep.[1] Other side effects may include abuse, psychosis, suicide, and Stevens-Johnson syndrome.[1] Use in pregnancy may harm the baby.[3] It is the (R)-(−)-enantiomer of modafinil.[1]

It was approved for medical use in the United States in 2007.[4] It is available as a generic medication.[1] In the United States a month of 250 mg pills costs about 32 USD as of 2022.[5] In the United States it is a schedule IV controlled substance.[1]

References[edit]

  1. ^ a b c d e f g h i j k "Modafinil". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 12 February 2021. Retrieved 16 January 2022.
  2. ^ a b "Armodafinil Monograph for Professionals". Drugs.com. Archived from the original on 14 August 2021. Retrieved 16 January 2022.
  3. ^ "Armodafinil (Nuvigil) Use During Pregnancy". Drugs.com. Archived from the original on 2021-02-05. Retrieved 2022-01-16.
  4. ^ "DailyMed - ARMODAFINIL tablet". dailymed.nlm.nih.gov. Archived from the original on 16 January 2022. Retrieved 16 January 2022.
  5. ^ "Armodafinil Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 10 October 2020. Retrieved 16 January 2022.
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